Anodyne No. 22 Men’s Sport Runner – Lightweight Performance with Everyday Therapeutic Support
The Anodyne No. 22 Men’s Sport Runner is built for men who want a sleek, athletic shoe that delivers comfort, stability, and therapeutic support throughout the day. Designed to handle everything from brisk walks to busy daily routines, this runner blends performance-inspired styling with thoughtful construction that supports healthy movement—mile after mile, step after step.
The design starts with a clean, streamlined athletic silhouette that looks fast, modern, and versatile. Easy to pair with activewear or casual outfits, the No. 22 feels equally at home during workouts, errands, or long days on your feet. Slip it on and you’ll immediately notice the balanced fit, soft interior padding, and smooth linings that provide comfort without unnecessary bulk.

Underfoot, a cushioned midsole absorbs impact and helps reduce strain on heels, joints, and the lower body. This shock-absorbing support promotes smoother transitions and helps minimize fatigue during extended wear. The removable cushioned insole adds plush comfort while allowing space for custom orthotics, making it easy to personalize your fit and support.
Designed with extra-depth construction, the Sport Runner accommodates swelling, high insteps, and sensitive foot conditions without feeling oversized. This makes the No. 22 a reliable choice for men managing plantar fasciitis, neuropathy, arthritis, or general foot discomfort—especially when long hours of movement are part of your day.

Breathable materials promote airflow to help keep feet cooler and more comfortable, even during increased activity. The flexible forefoot supports a natural running and walking motion, while the durable outsole provides dependable traction across a variety of indoor and outdoor surfaces for confident footing wherever your day takes you.
The Anodyne No. 22 Men’s Sport Runner delivers the look of a modern athletic shoe with the feel of therapeutic support built in. Lightweight, supportive, and designed for movement, it’s a dependable choice for men who want to stay active without sacrificing comfort.
Run your day. Stay supported. Move confidently in the No. 22.
HCPCS: A5500










